Objective. To assess oncological safety of lipofilling in patients with breast cancer. Material and methods. The article is based on the analysis of foreign data on lipofilling of the mammary gland in patients with breast cancer. Results. Numerous studies demonstrate the regenerative effects of free adipose tissue after radiotherapy. Most likely, this is due to high content of mesenchymal stem cells in fat transplants. Their amount varies depending on the lipografting procedure. There are few data about the interaction of fatty aspirate and «dormant» tumor cells despite the widespread use of this method around the world. It is extremely important to establish the factors influencing the risk of cancer recurrence during transplantation of free autologous adipose tissue. Conclusion. Subgroup analysis showed that low-grade tumor with positive lymph node status is a risk factor for breast cancer recurrence after lipofilling.

Keywords. breast cancer, lipofilling, reconstructive plastic surgery, relapse